This is meant to assist those looking for clinical trails for the newly diagnosed child with a DIPG. Since trials are continually being updated, added and closed all information should be independently confirmed as it may no longer be accurate. You can find out more information about clinical trials at-http://www.justonemoreday.org/TreatingPontineGliomas/ClinicalTrials.html
Radiologic Study (can be in conjunction with other therapeutic studies)Proton Nuclear Magnatic Resonance Spectroscopic Imaging Compared with Fludeoxyglucose F 18 Positron Emission Tomography Scanning in Determining Biologic or Metabolic Tumor Activity in Young Persons with Brain Tumors
Eligible Age- 1 to 21
Location- Bethesda, MD (NIH)
Study Chair- Katherine Warren, MD
http://clinicaltrials.gov/ct2/show/NCT00070512?term=Newly+Diagnosed+Glioma+Children&recr=Open&rank=26
Open Therapeutic TrialsArsenic Trioxide and Radiation Therapy in Treating Young Patients With Newly Diagnosed Gliomas
Phase 1
Eligible Age- 3 to 21
Location- Johns Hopkins, MD
Study Chair- Kenneth J Cohen, MD
http://clinicaltrials.gov/ct2/show/NCT00095771?term=arsenic+Trioxide+brain+tumor&rank=3
Interferon Alfa After Radiation Therapy in Treating Young Patients With Glioma
Phase 2
Eligible Age- up to 21
Study Chair- Katherine Warren, MD
Location- Bethesda, MD (NIH)
http://clinicaltrials.gov/ct2/show/NCT00041145?term=pontine+glioma&rank=10
Combination Chemotherapy and Radiation Therapy With and Without Methotrexate in Treating Young Patients with Newly Diagnosed Gliomas
Phase 3
Eligible Age- 3 to 18
Study Chair- Christoph Kramm, MD
Location- MD Anderson (sponsor from Germany)http://clinicaltrials.gov/ct2/show/NCT00278278?term=pontine+glioma&rank=8
A Study of Bevacizumab Therapy in Patients With Newly Diagnosed High Grade Gliomas and Diffuse Intrinsic Pontine Gliomas
Phase 1//2
Eligible Age- 3 to 30
Principal Investigator- Maryam Fouladi, MDUS
Location- Cincinnati, Ohio
http://clinicaltrials.gov/ct2/show/NCT00890786?term=pontine+glioma&rank=2
Temozolomide and Radiation Therapy in Treating Young Patients with Pontine Glioma
Phase 3
Eligible Age- 2 to 21
Study Chair- Simon Bailey, MD
Locations- Multiple throughout the UK
http://clinicaltrials.gov/ct2/show/NCT00514397?term=pontine+glioma&rank=5
Vandetanib and Radiation Therapy in Treating Young Patients with Newly Diagnosed Diffuse Brainstem Glioma
Phase 1
Eligible Age- 2 to 20
Study Chair- Alberto Broniscer, MD
Location- St Jude, Memphis, TN
http://clinicaltrials.gov/ct2/show/NCT00472017?term=St+Jude+brainstem&rank=2
Capceitabine and Radiation Therapy in Treating Young Patients with Newly Diagnosed, Nonmetastatic Brain Stem Glioma or High Grade Glioma
Phase 1
Eligible Age- 3 to 21
Study Chair- Susan Blaney, MD
Location – PBTC sites in the US
http://clinicaltrials.gov/ct2/show/NCT00357253?term=St+Jude+brainstem&rank=10
Vaccine Therapy in Treating Young Patients With Newly Diagnosed or Recurrent Glioma
Phase 1
Eligible Age- 3 to 20
Study Chair- Regina Jakacki, MD
Location- Pittsburgh, Pennsylvania
http://clinicaltrials.gov/ct2/show/NCT00862199?term=Newly+Diagnosed+Glioma&recr=Open&rank=7
Trials on Clinicaltrials.gov but Not Yet Opened for the Newly Diagnosed Child with a DIPG (at the time of being placed on the site but could be now)
Valproic Acid and Radiation Followed by Maintenance Valproic Acid and Bevacizumab in Children with High Grade Gliomas
Phase-1
Eligible Age- 3 to 21
Study Chair- Susan Blaney MD
Location- Texas Children’s
http://clinicaltrials.gov/ct2/show/NCT00879437?term=Newly+Diagnosed+Glioma+Children&recr=Open&rank=10
As of May 25, 2009
